2026.6.1

We are delighted to announce that our collaborative study with Prof. Hiroyasu Nakano's group at Toho University has been published in Communications Biology.
In this study, we showed that the inflammatory cytokine IL-33 is released from dying cells through a NINJ1-dependent plasma membrane rupture mechanism. Using real-time single-cell imaging, we further revealed that the timing of IL-33 release varies substantially among individual cells and cell death pathways.
These findings provide new insights into how dying cells regulate inflammatory signaling and may help advance our understanding of inflammation-related diseases.

https://www.nature.com/articles/s42003-026-10300-1
[Press release] https://www.toho-u.ac.jp/press/2026_index/20260601-1612.html
[EurekAlert!] https://www.eurekalert.org/news-releases/1129457